Do HOXB9 and COL1A1 genes play a role in congenital dislocation of the hip? Study in a Caucasian population.

@article{Rouault2009DoHA,
  title={Do HOXB9 and COL1A1 genes play a role in congenital dislocation of the hip? Study in a Caucasian population.},
  author={Karen Rouault and Virginie Scotet and Sandrine Autret and François Gaucher and Fr{\'e}d{\'e}ric Dubrana and D{\"o}me Tanguy and C Yaacoub El Rassi and Bertrand Fenoll and Claude F{\'e}rec},
  journal={Osteoarthritis and cartilage},
  year={2009},
  volume={17 8},
  pages={1099-105}
}
OBJECTIVE Congenital dislocation of the hip (CDH), which is one of the most common congenital skeletal disorders, corresponds to an abnormal seating of the femoral head in the acetabulum. It is commonly admitted that CDH presents a genetic component. However, little is known about the genetic factors involved. This study aimed to determine the role of two potential candidate genes on chromosome 17 in CDH: HOXB9 (involved in limb embryonic development) and COL1A1 (involved in joint laxity… CONTINUE READING

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