Do HOXB13 and P63 have a role in differentiating poorly differentiated prostatic carcinoma from urothelial high-grade carcinoma?

@article{Alshenawy2015DoHA,
  title={Do HOXB13 and P63 have a role in differentiating poorly differentiated prostatic carcinoma from urothelial high-grade carcinoma?},
  author={Hanan Alsaeid Alshenawy and Eman Mohammed Saied},
  journal={APMIS : acta pathologica, microbiologica, et immunologica Scandinavica},
  year={2015},
  volume={123 9},
  pages={772-8}
}
Poorly differentiated prostatic carcinoma may overlap with high-grade urothelial carcinoma; a distinction is a must as treatments differ. This study aims to evaluate traditional (PSA and HMWCK) and relatively novel (P63 and HOXB13) markers in distinguishing them; and to evaluate their role in the diagnosis of challenging cases. Sections from: diagnosed group includes 65 prostatic and urothelial carcinoma cases were stained with PSA, HMWCK, P63, and HOXB13. Sensitivity, specificity, and accuracy… CONTINUE READING

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