• DOI:10.1345/aph.19118
Corpus ID: 21151432

Do Ethanol and Metronidazole Interact to Produce a Disulfiram-Like Reaction?

@inproceedings{Williams2000DoEA,
  title={Do Ethanol and Metronidazole Interact to Produce a Disulfiram-Like Reaction?},
  author={C. Williams and K. Woodcock},
  booktitle={The Annals of pharmacotherapy},
  year={2000}
}

• C. Williams, K. Woodcock
• Published in The Annals of pharmacotherapy 2000
• Medicine

OBJECTIVE: To obtain and evaluate evidence about the supposed disulfiram-like interaction between metronidazole and ethanol. DATA SOURCES: MEDLINE search from January 1964 to June 1999, using the terms metronidazole, ethanol, and drug reaction. DATA SYNTHESIS: The manufacturer's warnings include a disulfiram-like reaction between metronidazole and ethanol. However, review of reports published between 1969 and 1982 produced no convincing evidence that this reaction exists. Six case reports… Expand

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