Do Ethanol and Metronidazole Interact to Produce a Disulfiram-Like Reaction?

@inproceedings{Williams2000DoEA,
  title={Do Ethanol and Metronidazole Interact to Produce a Disulfiram-Like Reaction?},
  author={C. Williams and K. Woodcock},
  booktitle={The Annals of pharmacotherapy},
  year={2000}
}
OBJECTIVE: To obtain and evaluate evidence about the supposed disulfiram-like interaction between metronidazole and ethanol. DATA SOURCES: MEDLINE search from January 1964 to June 1999, using the terms metronidazole, ethanol, and drug reaction. DATA SYNTHESIS: The manufacturer's warnings include a disulfiram-like reaction between metronidazole and ethanol. However, review of reports published between 1969 and 1982 produced no convincing evidence that this reaction exists. Six case reports… Expand
38 Citations

Paper Mentions

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