Do Ethanol and Metronidazole Interact to Produce a Disulfiram-Like Reaction?
@inproceedings{Williams2000DoEA, title={Do Ethanol and Metronidazole Interact to Produce a Disulfiram-Like Reaction?}, author={C. Williams and K. Woodcock}, booktitle={The Annals of pharmacotherapy}, year={2000} }
OBJECTIVE: To obtain and evaluate evidence about the supposed disulfiram-like interaction between metronidazole and ethanol. DATA SOURCES: MEDLINE search from January 1964 to June 1999, using the terms metronidazole, ethanol, and drug reaction. DATA SYNTHESIS: The manufacturer's warnings include a disulfiram-like reaction between metronidazole and ethanol. However, review of reports published between 1969 and 1982 produced no convincing evidence that this reaction exists. Six case reports… Expand
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