Do Electronic Cigarettes Have a Role in Tobacco Cessation?

@article{Franks2018DoEC,
  title={Do Electronic Cigarettes Have a Role in Tobacco Cessation?},
  author={Andrea S. Franks and Karen R. Sando and Sarah E. McBane},
  journal={Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy},
  year={2018},
  volume={38}
}
Tobacco use continues to be a major cause of morbidity and mortality. Even with behavioral and pharmacologic treatment, long‐term tobacco cessation rates are low. Electronic nicotine delivery systems, commonly referred to as electronic cigarettes or e‐cigarettes, are increasingly used for tobacco cessation. Because e‐cigarettes are widely used in this setting, health care professionals need to know if they are safe and effective. The purpose of this article is to review literature regarding use… 
13 Citations
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Electronic cigarettes seem to worsen asthma symptoms and the rate and severity of exacerbations in asthmatics who are current vapers, whilst evidence suggests that its effectiveness as a smoking cessation tool might be limited.
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TLDR
It is suggested that nicotine may have negative effects on both cellular viability and cellular proliferation among cancerous and non-cancerous cells, and these effects appear to become more pronounced over time, suggesting that short-term exposure to vaping solutions comprised of water with small amounts of nicotine may be sufficient to induce these effects.
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TLDR
Pharmacotherapy combined with behavioral interventions delivered via mHealth may be a promising strategy to help COPD smokers quit, but the overall quality of the current studies is poor, making it challenging for clinicians to make informed decisions.
Critical appraisal of the European Union Scientific Committee on Health, Environmental and Emerging Risks (SCHEER) Preliminary Opinion on electronic cigarettes
TLDR
Evidence is provided that the Opinion’s conclusions are not adequately backed up by scientific evidence and did not discuss the potential health benefits of using alternative combustion-free nicotine-containing products as substitute for tobacco cigarettes.
Carbon Monoxide and Small Hydrocarbon Emissions from Sub-ohm Electronic Cigarettes.
TLDR
This study presents for the first time the mouthpiece emissions of carbon monoxide and small hydrocarbon gases, in addition to carbonyls, from a rebuildable atomizer sub-ohm device (SOD), and casts doubt on the validity of CO as a biomarker to distinguish ECIG from tobacco cigarette use.
Cancer Prevention Strategies for Women.
TLDR
Primary prevention strategies-those aimed at reducing the risk of developing cancer-as well as secondary prevention strategies -measures aimed at the early detection of disease are examined.
The customizable e-cigarette resistance influences toxicological outcomes: lung degeneration, inflammation and oxidative stress-induced in a rat model.
TLDR
The manipulation of e-cig resistance influences the carbonyls production from non-nicotine vapour and the oxidative and inflammatory status in a rat model, and suggests that certain "tips for vaping safety" cannot be established.
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References

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TLDR
If patients who smoke are unwilling to quit or cannot succeed using evidence-based approaches, e-cigarettes may be an option to be considered after discussing the limitations of current knowledge.
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TLDR
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TLDR
The main outcome measure was abstinence from smoking after at least six months follow-up, and was the most rigorous definition available (continuous, biochemically validated, longest follow- up).
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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