DjPiwi-1, a member of the PAZ-Piwi gene family, defines a subpopulation of planarian stem cells

@article{Rossi2006DjPiwi1AM,
  title={DjPiwi-1, a member of the PAZ-Piwi gene family, defines a subpopulation of planarian stem cells},
  author={Leonardo Maria De Rossi and Alessandra Salvetti and Annalisa Lena and Renata Batistoni and Paolo Deri and C Pugliesi and Elena Loreti and Vittorio Gremigni},
  journal={Development Genes and Evolution},
  year={2006},
  volume={216},
  pages={335-346}
}
Planarian regeneration, based upon totipotent stem cells, the neoblasts, provides a unique opportunity to study in vivo the molecular program that defines a stem cell. In this study, we report the identification of DjPiwi-1, a planarian homologue of Drosophila Piwi. Expression analysis showed that DjPiwi-1 transcripts are preferentially accumulated in small cells distributed along the midline of the dorsal parenchyma. DjPiwi-1 transcripts were not detectable after X-ray irradiation by whole… CONTINUE READING
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