Division of mitochondria requires a novel DNM1-interacting protein, Net2p.

  title={Division of mitochondria requires a novel DNM1-interacting protein, Net2p.},
  author={Kara L Cerveny and J. Michael McCaffery and Robert E. Jensen},
  journal={Molecular biology of the cell},
  volume={12 2},
Mitochondria are dynamic organelles that undergo frequent division and fusion, but the molecular mechanisms of these two events are not well understood. Dnm1p, a mitochondria-associated, dynamin-related GTPase was previously shown to mediate mitochondrial fission. Recently, a genome-wide yeast two-hybrid screen identified an uncharacterized protein that interacts with Dnm1p. Cells disrupted in this new gene, which we call NET2, contain a single mitochondrion that consists of a network formed by… CONTINUE READING

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