Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections

@article{Guilliams2013DivisionOL,
  title={Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections},
  author={Martin Guilliams and Bart M. Lambrecht and Hamida Hammad},
  journal={Mucosal Immunology},
  year={2013},
  volume={6},
  pages={464-473}
}
The lung is highly exposed to the external environment. For this reason, the lung needs to handle a number of potential threats present in inhaled air such as viruses or bacteria. Dendritic cells (DCs) and macrophages (MFs) play an important role in orchestrating the immune responses to these challenges. The severe lung inflammation caused by some pathogens poses a unique challenge to the immune system: the potential insult must be eliminated rapidly whereas tissue inflammation must be… CONTINUE READING

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