Division and subtraction by distinct cortical inhibitory networks in vivo

@article{Wilson2012DivisionAS,
  title={Division and subtraction by distinct cortical inhibitory networks in vivo},
  author={Nathan R. Wilson and Caroline A. Runyan and F. L. Wang and Mriganka Sur},
  journal={Nature},
  year={2012},
  volume={488},
  pages={343-348}
}
Brain circuits process information through specialized neuronal subclasses interacting within a network. Revealing their interplay requires activating specific cells while monitoring others in a functioning circuit. Here we use a new platform for two-way light-based circuit interrogation in visual cortex in vivo to show the computational implications of modulating different subclasses of inhibitory neurons during sensory processing. We find that soma-targeting, parvalbumin-expressing (PV… CONTINUE READING
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