Division and differentiation of isolated CNS blast cells in microculture

  title={Division and differentiation of isolated CNS blast cells in microculture},
  author={S. Temple},
  • S. Temple
  • Published 1989
  • Biology, Medicine
  • Nature
  • THE mechanism of transformation of the overtly similar cells of the neural plate into the numerous and diverse cell types of the mature vertebrate central nervous system (CNS)1 can better be understood by studying the clonal development of isolated CNS precursor cells. Here I describe a culture system in which blast cells (cells capable of division) isolated from embryonic day 13.5–14.5 rat forebrain can divide and differentiate into a variety of clonal types. Most clones contain only neurons… CONTINUE READING

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