Diversity within the pRb pathway: is there a code of conduct?

Abstract

The failure of cell proliferation to be properly regulated is a hallmark of tumourigenesis. The retinoblastoma protein (pRb) pathway represents a key component in the regulation of the cell cycle and tumour suppression. Recent findings have revealed new levels of complexity reflecting a repertoire of post-translational modifications that occur on pRb… (More)
DOI: 10.1038/onc.2011.603

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