• DOI:10.1007/s00424-003-1110-3
Corpus ID: 5691463

Diversity of the mammalian sodium/proton exchanger SLC9 gene family

@article{Orlowski2004DiversityOT,
  title={Diversity of the mammalian sodium/proton exchanger SLC9 gene family},
  author={J. Orlowski and S. Grinstein},
  journal={Pfl{\"u}gers Archiv},
  year={2004},
  volume={447},
  pages={549-565}
}

J. Orlowski, S. Grinstein

Published 2004

Biology, Medicine

Pflügers Archiv

Sodium/proton antiporters or exchangers (NHE) are integral membrane proteins present in most, if not all, living organisms. In mammals, these transporters chiefly catalyze the electroneutral exchange of Na+ and H+ down their respective concentration gradients and are crucial for numerous physiological processes, ranging from the fine control of intracellular pH and cell volume to systemic electrolyte, acid-base and fluid volume homeostasis. NHE activity also facilitates the progression of other… CONTINUE READING

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