Diversity of structure and function of response regulator output domains.

@article{Galperin2010DiversityOS,
  title={Diversity of structure and function of response regulator output domains.},
  author={Michael Y. Galperin},
  journal={Current opinion in microbiology},
  year={2010},
  volume={13 2},
  pages={150-9}
}
Response regulators (RRs) within two-component signal transduction systems control a variety of cellular processes. Most RRs contain DNA-binding output domains and serve as transcriptional regulators. Other RR types contain RNA-binding, ligand-binding, protein-binding or transporter output domains and exert regulation at the transcriptional, post-transcriptional or post-translational levels. In a significant fraction of RRs, output domains are enzymes that themselves participate in signal… CONTINUE READING
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