Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin.

@article{Wakamatsu2006DiversityOP,
  title={Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin.},
  author={Kazumasa Wakamatsu and Renny J Kavanagh and Ana Luisa Kadekaro and Silva Terzieva and Richard A Sturm and Sancy A. Leachman and Zalfa A Abdel-Malek and Shosuke Ito},
  journal={Pigment cell research},
  year={2006},
  volume={19 2},
  pages={154-62}
}
Cultured human melanocytes differ tremendously in visual pigmentation, and recapitulate the pigmentary phenotype of the donor's skin. This diversity arises from variation in type as well as quantity of melanin produced. Here, we measured contents of eumelanin (EM) and pheomelanin (PM) in 60 primary human melanocyte cultures (51 neonatal and nine adults), and correlated some of these values with the respective activity and protein levels of tyrosinase, and the melanocortin-1 receptor (MC1R… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 43 extracted citations

Similar Papers

Loading similar papers…