Diversity of insect nicotinic acetylcholine receptor subunits.

  title={Diversity of insect nicotinic acetylcholine receptor subunits.},
  author={Andrew K Jones and David B Sattelle},
  journal={Advances in experimental medicine and biology},
Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that mediate fast synaptic transmission in the insect nervous system and are targets of a major group of insecticides, the neonicotinoids. They consist of five subunits arranged around a central ion channeL Since the subunit composition determines the functional and pharmacological properties of the receptor the presence of nAChR families comprising several subunit-encodinggenes provides a molecular basis for broad… CONTINUE READING


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