Diversity of immune strategies explained by adaptation to pathogen statistics

@article{Mayer2016DiversityOI,
  title={Diversity of immune strategies explained by adaptation to pathogen statistics},
  author={Andreas Mayer and Thierry Mora and Olivier Rivoire and Aleksandra M. Walczak},
  journal={Proceedings of the National Academy of Sciences},
  year={2016},
  volume={113},
  pages={8630 - 8635}
}
  • A. Mayer, T. Mora, +1 author A. Walczak
  • Published 27 November 2015
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
Significance Organisms possess many mechanisms for protecting themselves from pathogens. In addition to the well-studied innate and adaptive immune systems of vertebrates, recently discovered mechanisms such as CRISPR immunity in prokaryotes diversify the known modes of information processing used in immune protection. By classifying these different systems in terms of their rules of heritability and response to the environment, we propose a mathematical framework that recapitulates the… 
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