Diversity of glycine receptors in the mouse retina: localization of the alpha3 subunit.

@article{Haverkamp2003DiversityOG,
  title={Diversity of glycine receptors in the mouse retina: localization of the alpha3 subunit.},
  author={Silke Haverkamp and Ulrike M{\"u}ller and Kirsten Harvey and Robert J Harvey and Heinrich Betz and Heinz W{\"a}ssle},
  journal={The Journal of comparative neurology},
  year={2003},
  volume={465 4},
  pages={524-39}
}
Glycine receptors (GlyRs) and their role in retinal circuitry were analyzed immunocytochemically in wild-type and GlyR alpha3 subunit-deficient (Glra3(-/-)) mouse retinae. GlyRs are localized in the inner plexiform layer in brightly fluorescent puncta, which are likely to represent postsynaptically clustered GlyRs. Approximately one third of the clusters were found to contain the alpha1 subunit, and half possessed the alpha3 subunit. However, these two GlyR isoforms were localized at different… CONTINUE READING

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