Diversity of enteroendocrine cells investigated at cellular and subcellular levels: the need for a new classification scheme

@article{Fothergill2018DiversityOE,
  title={Diversity of enteroendocrine cells investigated at cellular and subcellular levels: the need for a new classification scheme},
  author={Linda J. Fothergill and John Barton Furness},
  journal={Histochemistry and Cell Biology},
  year={2018},
  volume={150},
  pages={693-702}
}
Enteroendocrine cells were historically classified by a letter code, each linked to a single hormone, deduced to be the only hormone produced by the cell. One type, the L cell, was recognised to store and secrete two products, peptide YY (PYY) and glucagon-related peptides. Many other exceptions to the one-cell one-hormone classifications have been reported over the last 40 years or so, and yet the one-hormone dogma has persisted. In the last 6 years, a plethora of data has appeared that makes… CONTINUE READING
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