Diversity of Potassium Channel Ligands: Focus on Scorpion Toxins

@article{Kuzmenkov2015DiversityOP,
  title={Diversity of Potassium Channel Ligands: Focus on Scorpion Toxins},
  author={Alexey I. Kuzmenkov and Eugene V. Grishin and Alexander A. Vassilevski},
  journal={Biochemistry (Moscow)},
  year={2015},
  volume={80},
  pages={1764-1799}
}
Potassium (K+) channels are a widespread superfamily of integral membrane proteins that mediate selective transport of K+ ions through the cell membrane. They have been found in all living organisms from bacteria to higher multicellular animals, including humans. Not surprisingly, K+ channels bind ligands of different nature, such as metal ions, low molecular mass compounds, venom-derived peptides, and antibodies. Functionally these substances can be K+ channel pore blockers or modulators… CONTINUE READING
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