Diversity of Mitochondrial Pathology in a Mouse Model of Axonal Degeneration in Synucleinopathies

Abstract

There is mounting evidence for a role of mitochondrial dysfunction in the pathogenesis of α -synucleinopathies such as Parkinson's disease (PD) and dementia with Lewy bodies (DLB). In particular, recent studies have demonstrated that failure of mitochondrial quality control caused by loss of function of the PTEN-induced kinase 1 (PINK1, PARK6) Parkin (PARK2… (More)
DOI: 10.1155/2013/817807

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Cite this paper

@inproceedings{Sekigawa2013DiversityOM, title={Diversity of Mitochondrial Pathology in a Mouse Model of Axonal Degeneration in Synucleinopathies}, author={Akio Sekigawa and Yoshiki Takamatsu and Kazunari Sekiyama and Takato Takenouchi and Shuei Sugama and Masaaki Waragai and Masayo Fujita and Makoto Hashimoto}, booktitle={Oxidative medicine and cellular longevity}, year={2013} }