Diversity of G proteins in signal transduction

@article{Simon1991DiversityOG,
  title={Diversity of G proteins in signal transduction},
  author={Michael G. Simon and MP Strathmann and N Gautam},
  journal={Science},
  year={1991},
  volume={252},
  pages={802 - 808}
}
The heterotrimeric guanine nucleotide-binding proteins (G proteins) act as switches that regulate information processing circuits connecting cell surface receptors to a variety of effectors. The G proteins are present in all eukaryotic cells, and they control metabolic, humoral, neural, and developmental functions. More than a hundred different kinds of receptors and many different effectors have been described. The G proteins that coordinate receptor-effector activity are derived from a large… 
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