Diversity in a variable-number tandem repeat from Yersinia pestis.

  title={Diversity in a variable-number tandem repeat from Yersinia pestis.},
  author={Diana Adair and Patricia L. Worsham and Karen K. Hill and Alexandra M Klevytska and Paul J. Jackson and Arthur M. Friedlander and Paul S Keim},
  journal={Journal of clinical microbiology},
  volume={38 4},
We have identified a tetranucleotide repeat sequence, (CAAA)(N), in the genome of Yersinia pestis, the causative agent of plague. This variable-number tandem repeat (VNTR) region has nine alleles and great diversity (calculated as 1 minus the sum of the squared allele frequencies) (diversity value, 0.82) within a set of 35 diverse Y. pestis strains. In contrast, the nucleotide sequence of the lcrV (low-calcium-response) gene differed only slightly among these strains, having a haplotype… CONTINUE READING