Diversity in MHC class II antigen presentation.

@article{Robinson2002DiversityIM,
  title={Diversity in MHC class II antigen presentation.},
  author={John H. Robinson and Alexei A. Delvig},
  journal={Immunology},
  year={2002},
  volume={105 3},
  pages={
          252-62
        }
}
Processing exogenous and endogenous proteins for presentation by major histocompatibility complex (MHC) molecules to T cells is the defining function of antigen-presenting cells (APC) as major regulatory cells in the acquired immune response. MHC class II-restricted antigen presentation to CD4 T cells is achieved by an essentially common pathway that is subject to variation with regard to the location and extent of degradation of protein antigens and the site of peptide binding to MHC class II… CONTINUE READING
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