Diversity and signature of small RNA in different bodily fluids using next generation sequencing

@inproceedings{ElMogy2018DiversityAS,
  title={Diversity and signature of small RNA in different bodily fluids using next generation sequencing},
  author={Mohamed M. El-Mogy and Bernard O. Lam and Taha Alexander Haj-Ahmad and Shannon L. McGowan and Darrick Yu and Lucas Nosal and Nezar Rghei and Pam Roberts and Yousef Haj-Ahmad},
  booktitle={BMC Genomics},
  year={2018}
}
Small RNAs are critical components in regulating various cellular pathways. These molecules may be tissue-associated or circulating in bodily fluids and have been shown to associate with different tumors. Next generation sequencing (NGS) on small RNAs is a powerful tool for profiling and discovery of microRNAs (miRNAs). In this study, we isolated total RNA from various bodily fluids: blood, leukocytes, serum, plasma, saliva, cell-free saliva, urine and cell-free urine. Next, we used Illumina’s… CONTINUE READING
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