Diversity and evolution of the highly polymorphic tandem repeat LEI0258 in the chicken MHC-B region

@article{Chazara2013DiversityAE,
  title={Diversity and evolution of the highly polymorphic tandem repeat LEI0258 in the chicken MHC-B region},
  author={Olympe Chazara and C S Chang and Nicolas Bruneau and Khalid Benabdeljelil and Jean-Claude Fotsa and Boniface Baboreka Kayang and N’Goran E. Loukou and Richard Osei-Amponsah and Valentine C Yapi-Gnaore and Issaka A. K. Youssao and Chih-Feng Chen and M. H. Pinard-van der Laan and Mich{\`e}le Tixier-Boichard and Bertrand Bed’hom},
  journal={Immunogenetics},
  year={2013},
  volume={65},
  pages={447-459}
}
The chicken major histocompatibility complex (MHC) is located on the microchromosome 16 and is described as the most variable region in the genome. The genes of the MHC play a central role in the immune system. Particularly, genes encoding proteins involved in the antigen presentation to T cells. Therefore, describing the genetic polymorphism of this region is crucial in understanding host–pathogen interactions. The tandem repeat LEI0258 is located within the core area of the B region of the… CONTINUE READING