Diversity and evolution of the green fluorescent protein family.

  title={Diversity and evolution of the green fluorescent protein family.},
  author={Yulii A. Labas and Nadya G. Gurskaya and Yurii G Yanushevich and Arkady F. Fradkov and Konstantin A. Lukyanov and Sergey A. Lukyanov and Mikhail V Matz},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={99 7},
The family of proteins homologous to the green fluorescent protein (GFP) from Aequorea victoria exhibits striking diversity of features, including several different types of autocatalytically synthesized chromophores. Here we report 11 new members of the family, among which there are 3 red-emitters possessing unusual features, and discuss the similarity relationships within the family in structural, spectroscopic, and evolutionary terms. Phylogenetic analysis has shown that GFP-like proteins… CONTINUE READING


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