Diversity and evolution of mitochondrial RNA editing systems.

  title={Diversity and evolution of mitochondrial RNA editing systems.},
  author={Michael W. Gray},
  journal={IUBMB life},
  volume={55 4-5},
'RNA editing' describes the programmed alteration of the nucleotide sequence of an RNA species, relative to the sequence of the encoding DNA. The phenomenon encompasses two generic patterns of nucleotide change, 'insertion/deletion' and 'substitution', defined on the basis of whether the sequence of the edited RNA is colinear with the DNA sequence that encodes it. RNA editing is mediated by a variety of pathways that are mechanistically and evolutionarily unrelated. Messenger, ribosomal… CONTINUE READING


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