Diversity and distribution of Microcystis (Cyanobacteria) oligopeptide chemotypes from natural communities studied by single-colony mass spectrometry.

@article{Welker2004DiversityAD,
  title={Diversity and distribution of Microcystis (Cyanobacteria) oligopeptide chemotypes from natural communities studied by single-colony mass spectrometry.},
  author={Martin H. Welker and Matthias Brunke and Karina Preussel and Indra Lippert and Hans von Döhren},
  journal={Microbiology},
  year={2004},
  volume={150 Pt 6},
  pages={
          1785-96
        }
}
Microcystis sp. has been recognized in recent years as a producer of a high number of secondary metabolites. Among these, peptides that are produced by the non-ribosomal peptide synthetase pathway often show bioactivity or are toxic to humans. The production of particular peptides is specific for individual Microcystis clones, allowing their characterization as chemotypes by analysing the peptidome. The authors studied the in situ diversity of peptides and chemotypes in Microcystis communities… 

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