Diverse types of dermatologic toxicities from immune checkpoint blockade therapy.

  title={Diverse types of dermatologic toxicities from immune checkpoint blockade therapy.},
  author={Jonathan L Curry and Michael T Tetzlaff and Priyadharsini Nagarajan and Carol R Drucker and Adi Diab and Sharon R Hymes and Madeleine Duvic and W J Hwu and Jennifer A Wargo and Carlos A Torres-Cabala and Ronald P. Rapini and Victor G Prieto},
  journal={Journal of cutaneous pathology},
  volume={44 2},
Immunomodulatory drugs that leverages host immune mechanisms to destroy tumor cells have been met with great promise in the treatment of cancer. Immunotherapy, targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death 1 (PD-1) receptor and its ligand (PD-L1) have shown tremendous improvements in the survival of patients with advanced solid tumors. However, the development of dermatologic toxicity (DT) is a consequence to immunotherapy. Review of published… CONTINUE READING
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