Diverse roles of extracellular calcium-sensing receptor in the central nervous system.

@article{Bandyopadhyay2010DiverseRO,
  title={Diverse roles of extracellular calcium-sensing receptor in the central nervous system.},
  author={Sanghamitra Bandyopadhyay and Jacob Tfelt-Hansen and Naibedya Chattopadhyay},
  journal={Journal of neuroscience research},
  year={2010},
  volume={88 10},
  pages={2073-82}
}
The G-protein-coupled calcium-sensing receptor (CaSR), upon activation by Ca(2+) or other physiologically relevant polycationic molecules, performs diverse functions in the brain. The CaSR is widely expressed in the central nervous system (CNS) and is characterized by a robust increase in its expression during postnatal brain development over adult levels throughout the CNS. Developmental increases in CaSR levels in brain correlate with myelinogenesis. Indeed, neural stem cells differentiating… CONTINUE READING

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