Diverse neuronal populations mediate local circuit excitation in area CA3 of developing hippocampus.

@article{Smith1995DiverseNP,
  title={Diverse neuronal populations mediate local circuit excitation in area CA3 of developing hippocampus.},
  author={Karen L. Smith and Donald H. Szarowski and James N. Turner and John W. Swann},
  journal={Journal of neurophysiology},
  year={1995},
  volume={74 2},
  pages={650-72}
}
1. Studies were undertaken to better understand why the developing hippocampus has a marked capacity to generate prolonged synchronized discharges when exposed to gamma-aminobutyric acid-A (GABAA) receptor antagonists. 2. Excitatory synaptic interactions were studied in small microdissected segments of hippocampal area CA3. Slices were obtained from 10- to 16-day-old rats. Application of the GABAA receptor antagonist penicillin produced prolonged synchronized discharges in minislices that were… CONTINUE READING

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