Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells.

@article{Nachmani2009DiverseHM,
  title={Diverse herpesvirus microRNAs target the stress-induced immune ligand MICB to escape recognition by natural killer cells.},
  author={Daphna Nachmani and Noam Stern-Ginossar and Ronit Sarid and Ofer Mandelboim},
  journal={Cell host & microbe},
  year={2009},
  volume={5 4},
  pages={
          376-85
        }
}
Herpesviruses are known for their persistent lifelong latent infection, which is made possible by their vast repertoire of immune-evasion strategies. We have previously shown that a human cytomegalovirus (HCMV) microRNA represses expression of the stress-induced Natural Killer (NK) cell ligand, MICB, to escape recognition and consequent elimination by NK cells. Here, we show functional conservation among diverse microRNAs derived from different herpesviruses, including HCMV, Kaposi's sarcoma… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 36 REFERENCES

Generation of a stable cell line producing high-titer self-inactivating lentiviral vectors.

  • Molecular therapy : the journal of the American Society of Gene Therapy
  • 2001
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

IdentificationofmicroRNAs of the herpesvirus family

S. Pfeffer, A. Sewer, +8 authors etal
  • Nat. Methods
  • 2005
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Cytomegalovirus immune evasion.

  • Current topics in microbiology and immunology
  • 2008
VIEW 2 EXCERPTS

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