Diverse fates of paralogs following segmental duplication of telomeric genes.

@article{Wong2004DiverseFO,
  title={Diverse fates of paralogs following segmental duplication of telomeric genes.},
  author={Andrew Thomas Wong and Eric J. Vallender and Konstantina Heretis and Yesim Ilkin and Bruce T. Lahn and Christa L. Martin and D. H. Ledbetter},
  journal={Genomics},
  year={2004},
  volume={84 2},
  pages={239-47}
}
The telomeric region of chromosome 9p is paralogous to the pericentromeric regions of chromosome 9 as well as to 2q13, the site of an ancestral telomere-telomere fusion. These paralogous regions span approximately 200 kb and contain seven transcriptional units, including the previously identified CBWD, FOXD4, PGM5, F379, CXYorf1, and two human Unigene clusters, Hs.115173 and Hs.189160. Within these gene duplicates, the number of expressed paralogous loci varies, from one in PGM5 to all three in… CONTINUE READING

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