Diverse environmental stresses elicit distinct responses at the level of pre-mRNA processing in yeast.

@article{Bergkessel2011DiverseES,
  title={Diverse environmental stresses elicit distinct responses at the level of pre-mRNA processing in yeast.},
  author={Megan Bergkessel and Gregg B Whitworth and C. Guthrie},
  journal={RNA},
  year={2011},
  volume={17 8},
  pages={1461-78}
}
Gene expression in eukaryotic cells is profoundly influenced by the post-transcriptional processing of mRNAs, including the splicing of introns in the nucleus and both nuclear and cytoplasmic degradation pathways. These processes have the potential to affect both the steady-state levels and the kinetics of changes to levels of intron-containing transcripts. Here we report the use of a splicing isoform-specific microarray platform to investigate the effects of diverse stress conditions on pre… CONTINUE READING
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