Diverse and essential roles of mammalian vacuolar-type proton pump ATPase: toward the physiological understanding of inside acidic compartments.

Abstract

The vacuolar-type H(+)-ATPases (V-ATPase) are a family of multi-subunit ATP-dependent proton pumps involved in a wide variety of physiological processes. They are present in endomembrane organelles such as vacuoles, lysosomes, endosomes, the Golgi apparatus, chromaffin granules and coated vesicles, and acidify the luminal pH of these intracellular… (More)

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Cite this paper

@article{SunWada2004DiverseAE, title={Diverse and essential roles of mammalian vacuolar-type proton pump ATPase: toward the physiological understanding of inside acidic compartments.}, author={Ge-hong Sun-Wada and Yoh Wada and Masamitsu Futai}, journal={Biochimica et biophysica acta}, year={2004}, volume={1658 1-2}, pages={106-14} }