Diverging functions among calreticulin isoforms in higher plants.

  title={Diverging functions among calreticulin isoforms in higher plants.},
  author={Lisa Thelin and Marek Mutwil and Marianne Sommarin and Staffan Persson},
  journal={Plant signaling & behavior},
  volume={6 6},
The ER chaperone calreticulin plays vital roles in numerous cellular processes, including Ca2+-homeostasis, apoptosis, and cell adhesion, in animal cells. Although calreticulin has been systematically characterized in animal cells, the focus has been on one of the isoforms. However, recent advances in the plant calreticulin field have revealed functional divergence of calreticulin isoforms. While two of the plant isoforms appear to work within a general ER chaperone framework, the third isoform… CONTINUE READING