Divergent in vitro and in vivo correlates of HIV-specific T-cell responses during onset of HIV viraemia.

@article{Kvale2005DivergentIV,
  title={Divergent in vitro and in vivo correlates of HIV-specific T-cell responses during onset of HIV viraemia.},
  author={Dag Kvale and Anne-Marte Bakken Kran and Maja A. Sommerfelt and J\orgen Nyhus and Ingebj\org Baksaas and Johan Nikolai Bruun and Birger S\orensen},
  journal={AIDS},
  year={2005},
  volume={19 6},
  pages={563-7}
}
BACKGROUND Cellular immune responses to HIV-1 have been examined mainly in peripheral blood mononuclear cells (PBMC). During onset of HIV replication and antigenaemia after discontinuation of highly active antiretroviral therapy (HAART), PBMC may theoretically contain HIV-specific T cells that are qualitatively and quantitatively different from specific T cells dominating in the tissues. PBMC responses throughout HIV immunotherapy trials may therefore be skewed during recurrent viraemia… CONTINUE READING

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Cellular immune responses associated with improved viral control after immunisation with a peptide-based HIV-1 immunotherapy candidate (Vacc-4x)

  • A-MB Kran, J Nyhus, MA Sommerfelt
  • AIDS Vaccine 2004 International Conference,
  • 2004
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