Divergent functions of lectin-like receptors on NK cells.

  title={Divergent functions of lectin-like receptors on NK cells.},
  author={James C. Ryan and William E. Seaman},
  journal={Immunological reviews},
NK cells express a superfamily of surface proteins that share a common structure: dimeric type II integral membrane proteins whose extracellular domains have structural features of C-type (calcium-dependent) lectins. These receptors are encoded in a single genetic region called the NK complex (NKC). The NKC encompasses several families of genes, including Ly-49 (in mice and rats), NKR-P1 (in mice, rats, and humans). NKG2 (in humans and rats), and CD94 (in humans). Different NKC receptors have… CONTINUE READING
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