Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish

@inproceedings{Abreu2017DivergentEO,
  title={Divergent effect of fluoxetine on the response to physical or chemical stressors in zebrafish},
  author={Murilo S. de Abreu and Ana Cristina Vendrametto Varrone Giacomini and Gessi Koakoski and Angelo L S Piato and Leonardo J G Barcellos},
  booktitle={PeerJ},
  year={2017}
}
Fluoxetine is a selective serotonin reuptake inhibitor that increases serotonin concentration in the central nervous system and modulates various systems, including the control of sympathetic outflow and the hypothalamus-pituitary-adrenal. However, it is not yet established whether fluoxetine can modulate the responses to stressors stimulants (physical or chemical) that trigger cortisol response in zebrafish. We demonstrate that fluoxetine blunts the response to physical stress, but not to… CONTINUE READING
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PeerJ, DOI 10.7717/peerj.3330

  • Abreu
  • 2017

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