Divergent adaptive and innate immunological responses are observed in humans following blunt trauma

@inproceedings{Kasten2009DivergentAA,
  title={Divergent adaptive and innate immunological responses are observed in humans following blunt trauma},
  author={Kevin Richard Kasten and Holly S. Goetzman and Maria R Reid and Alison M Rasper and Samuel G Adediran and Chad T. Robinson and Cindy M. Cave and Joseph S. Solomkin and Alex B. Lentsch and Jay A Johannigman and Charles C Caldwell},
  booktitle={BMC Immunology},
  year={2009}
}
The immune response to trauma has traditionally been modeled to consist of the systemic inflammatory response syndrome (SIRS) followed by the compensatory anti-inflammatory response syndrome (CARS). We investigated these responses in a homogenous cohort of male, severe blunt trauma patients admitted to a University Hospital surgical intensive care unit (SICU). After obtaining consent, peripheral blood was drawn up to 96 hours following injury. The enumeration and functionality of both myeloid… CONTINUE READING

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