Divergence time and population size in the lineage leading to modern humans.

@article{Takahata1995DivergenceTA,
  title={Divergence time and population size in the lineage leading to modern humans.},
  author={Naoyuki Takahata and Yoko Satta and Jan Klein},
  journal={Theoretical population biology},
  year={1995},
  volume={48 2},
  pages={
          198-221
        }
}
We have developed maximum likelihood (ML) methods for comparisons of nucleotide sequences from unlinked genomic regions. In the case of a single species, the ML method primarily estimates the effective population size (Ne) under both constant size and abrupt expansion conditions. In the case of two or three species, the ML method simultaneously estimates the species divergence time and the effective size of ancestral populations. This allows us to trace the evolutionary history of the human… CONTINUE READING

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