Divergence of Quaternary Structures Among Bacterial Flagellar Filaments

@article{Galkin2008DivergenceOQ,
  title={Divergence of Quaternary Structures Among Bacterial Flagellar Filaments},
  author={V. Galkin and X. Yu and Jakub Bielnicki and J. Heuser and C. Ewing and P. Guerry and E. Egelman},
  journal={Science},
  year={2008},
  volume={320},
  pages={382 - 385}
}
  • V. Galkin, X. Yu, +4 authors E. Egelman
  • Published 2008
  • Biology, Medicine
  • Science
  • It has been widely assumed that the atomic structure of the flagellar filament from Salmonella typhimurium serves as a model for all bacterial flagellar filaments given the sequence conservation in the coiled-coil regions responsible for polymerization. On the basis of electron microscopic images, we show that the flagellar filaments from Campylobacter jejuni have seven protofilaments rather than the 11 in S. typhimurium. The vertebrate Toll-like receptor 5 (TLR5) recognizes a region of… CONTINUE READING
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    References

    SHOWING 1-10 OF 26 REFERENCES
    Campylobacter flagella: not just for motility.
    • P. Guerry
    • Biology, Medicine
    • Trends in microbiology
    • 2007
    • 259
    Construction of bacterial flagella
    • 123
    Core mutations switch monomeric protein GB1 into an intertwined tetramer
    • 69
    • PDF
    Enhanced genome annotation using structural profiles in the program 3D-PSSM.
    • 1,533
    • PDF
    Evasion of Toll-like receptor 5 by flagellated bacteria.
    • 555
    • PDF