Divergence of Quaternary Structures Among Bacterial Flagellar Filaments

@article{Galkin2008DivergenceOQ,
  title={Divergence of Quaternary Structures Among Bacterial Flagellar Filaments},
  author={V. Galkin and X. Yu and Jakub Bielnicki and J. Heuser and C. Ewing and P. Guerry and E. Egelman},
  journal={Science},
  year={2008},
  volume={320},
  pages={382 - 385}
}
  • V. Galkin, X. Yu, +4 authors E. Egelman
  • Published 2008
  • Biology, Medicine
  • Science
  • It has been widely assumed that the atomic structure of the flagellar filament from Salmonella typhimurium serves as a model for all bacterial flagellar filaments given the sequence conservation in the coiled-coil regions responsible for polymerization. On the basis of electron microscopic images, we show that the flagellar filaments from Campylobacter jejuni have seven protofilaments rather than the 11 in S. typhimurium. The vertebrate Toll-like receptor 5 (TLR5) recognizes a region of… CONTINUE READING
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