Divergence of Quaternary Structures Among Bacterial Flagellar Filaments
@article{Galkin2008DivergenceOQ, title={Divergence of Quaternary Structures Among Bacterial Flagellar Filaments}, author={V. Galkin and X. Yu and Jakub Bielnicki and J. Heuser and C. Ewing and P. Guerry and E. Egelman}, journal={Science}, year={2008}, volume={320}, pages={382 - 385} }
It has been widely assumed that the atomic structure of the flagellar filament from Salmonella typhimurium serves as a model for all bacterial flagellar filaments given the sequence conservation in the coiled-coil regions responsible for polymerization. On the basis of electron microscopic images, we show that the flagellar filaments from Campylobacter jejuni have seven protofilaments rather than the 11 in S. typhimurium. The vertebrate Toll-like receptor 5 (TLR5) recognizes a region of… CONTINUE READING
Topics from this paper
100 Citations
An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete
- Medicine
- eLife
- 2020
- 4
- Highly Influenced
Molecular mechanisms of campylobacter infection.
- Biology, Medicine
- Current topics in microbiology and immunology
- 2009
- 66
- Highly Influenced
Functional characterization of flagellin glycosylation in Campylobacter jejuni 81-176.
- Biology, Medicine
- Journal of bacteriology
- 2009
- 96
- PDF
Atomic structure of the Campylobacter jejuni flagellar filament reveals how ε Proteobacteria escaped Toll-like receptor 5 surveillance
- Chemistry, Medicine
- Proceedings of the National Academy of Sciences
- 2020
Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions
- Biology, Medicine
- eLife
- 2018
- 23
- PDF
Problems in fitting high resolution structures into electron microscopic reconstructions
- Physics, Medicine
- HFSP journal
- 2008
- 11
An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete
- Chemistry
- 2020
Crystal Structure of Flagellar Export Chaperone FliS in Complex With Flagellin and HP1076 of Helicobacter pylori
- Chemistry, Medicine
- Frontiers in Microbiology
- 2020
- PDF
References
SHOWING 1-10 OF 26 REFERENCES
Helical structure of unidirectionally shadowed metal replicas of cyanide hydratase from Gloeocercospora sorghi.
- Chemistry, Medicine
- Journal of structural biology
- 2008
- 29
- PDF
The structure of bacterial ParM filaments
- Biology, Medicine
- Nature Structural &Molecular Biology
- 2007
- 84
A σ28-Regulated Nonflagella Gene Contributes to Virulence of Campylobacter jejuni 81-176
- Biology, Medicine
- Infection and Immunity
- 2006
- 49
- PDF
Variation in bacterial flagellins: from sequence to structure.
- Biology, Medicine
- Trends in microbiology
- 2006
- 119
- PDF
Evasion of Toll-like receptor 5 by flagellated bacteria.
- Biology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 2005
- 560
- PDF
Flagellar filaments of the deep-sea bacteria Idiomarina loihiensis belong to a family different from those of Salmonella typhimurium.
- Biology, Medicine
- Journal of molecular biology
- 2005
- 8
The limits of protein sequence comparison?
- Biology, Medicine
- Current opinion in structural biology
- 2005
- 82
- PDF
Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa.
- Biology, Medicine
- Trends in microbiology
- 2004
- 407
- PDF
Complete atomic model of the bacterial flagellar filament by electron cryomicroscopy
- Chemistry, Medicine
- Nature
- 2003
- 641
- PDF