Divergence of Quaternary Structures Among Bacterial Flagellar Filaments

  title={Divergence of Quaternary Structures Among Bacterial Flagellar Filaments},
  author={V. Galkin and X. Yu and Jakub Bielnicki and J. Heuser and C. Ewing and P. Guerry and E. Egelman},
  pages={382 - 385}
  • V. Galkin, X. Yu, +4 authors E. Egelman
  • Published 2008
  • Biology, Medicine
  • Science
  • It has been widely assumed that the atomic structure of the flagellar filament from Salmonella typhimurium serves as a model for all bacterial flagellar filaments given the sequence conservation in the coiled-coil regions responsible for polymerization. On the basis of electron microscopic images, we show that the flagellar filaments from Campylobacter jejuni have seven protofilaments rather than the 11 in S. typhimurium. The vertebrate Toll-like receptor 5 (TLR5) recognizes a region of… CONTINUE READING
    100 Citations
    An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete
    • 4
    • Highly Influenced
    Functional genomics of motile commensal intestinal bacteria
    • 1
    • Highly Influenced
    Molecular mechanisms of campylobacter infection.
    • 66
    • Highly Influenced
    Functional characterization of flagellin glycosylation in Campylobacter jejuni 81-176.
    • 96
    • PDF
    Atomic structure of the Campylobacter jejuni flagellar filament reveals how ε Proteobacteria escaped Toll-like receptor 5 surveillance
    Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions
    • 23
    • PDF
    Problems in fitting high resolution structures into electron microscopic reconstructions
    • 11
    Crystal Structure of Flagellar Export Chaperone FliS in Complex With Flagellin and HP1076 of Helicobacter pylori
    • PDF


    Campylobacter flagella: not just for motility.
    • P. Guerry
    • Biology, Medicine
    • Trends in microbiology
    • 2007
    • 261
    The structure of bacterial ParM filaments
    • 84
    Variation in bacterial flagellins: from sequence to structure.
    • 119
    • PDF
    Evasion of Toll-like receptor 5 by flagellated bacteria.
    • 560
    • PDF
    The limits of protein sequence comparison?
    • 82
    • PDF