Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine.

Abstract

TH (tyrosine hydroxylase) is the rate-limiting enzyme in the synthesis of catecholamines. The cat-2 gene of the nematode Caenorhabditis elegans is expressed in mechanosensory dopaminergic neurons and has been proposed to encode a putative TH. In the present paper, we report the cloning of C. elegans full-length cat-2 cDNA and a detailed biochemical… (More)
DOI: 10.1042/BJ20101561

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@article{Calvo2011DivergenceIE, title={Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine.}, author={Ana Calvo and Angel L Pey and Antonio Miranda-Vizuete and Anne Paulus D\oskeland and Aurora Martinez}, journal={The Biochemical journal}, year={2011}, volume={434 1}, pages={133-41} }