Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention.

  title={Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention.},
  author={Lance P. Longo and Todd M. Campbell and Sandra Hubatch},
  journal={Journal of addictive diseases},
  volume={21 2},
This pilot study evaluates the safety and efficacy of divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention. Sixteen patients in moderate alcohol withdrawal were randomized to receive a standard benzodiazepine detoxification, depakote detoxification, or depakote detox plus maintenance. Symptom reduction occurred more rapidly and consistently in the depakote treated patients than in the benzodiazepine control group, and at six-week follow up a greater percentage of patients… CONTINUE READING
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