Diva/BclB regulates differentiation by inhibiting NDPKB/Nm23H2-mediated neuronal differentiation in PC-12 cells

@inproceedings{Lim2012DivaBclBRD,
  title={Diva/BclB regulates differentiation by inhibiting NDPKB/Nm23H2-mediated neuronal differentiation in PC-12 cells},
  author={Jasmin Qian Ru Lim and Jia Lu and Bei Ping He},
  booktitle={BMC Neuroscience},
  year={2012}
}
Diva ( d eath i nducer binding to v Bcl-2 and A paf-1)/BclB is a Bcl-2 family member, which is known for its function in apoptosis. Diva/BclB has been shown to interact with NDPKB/Nm23H2, which is involved in cellular differentiation. Thus far, there has been no direct evidence of Diva/BclB having a role in differentiation. In the present study, we investigated the expression of Diva/BclB and NDPKB/Nm23H2 during differentiation in PC-12 cell line. Our results show that after differentiation… CONTINUE READING
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