Diurnal variation in concentrations of various markers of bone metabolism in dogs.

@article{Liesegang1999DiurnalVI,
  title={Diurnal variation in concentrations of various markers of bone metabolism in dogs.},
  author={Annette Liesegang and R A Reutter and M L Sassi and Juha P Risteli and Marius Kraenzlin and J L Riond and Marcel Wanner},
  journal={American journal of veterinary research},
  year={1999},
  volume={60 8},
  pages={949-53}
}
OBJECTIVE To evaluate diurnal variation in concentrations of selected markers of bone metabolism in dogs. ANIMALS Ten 3- to 4-year-old ovariectomized Beagles. PROCEDURE Blood and urine samples were obtained in the morning before dogs were fed (8 AM) and then at 2-hour intervals for 24 hours. This procedure was repeated 2 weeks later. Concentrations of osteocalcin (OC) and carboxy terminal telopeptide of type-I collagen (ICTP) were measured in serum, using a radioimmunoassay; concentrations… CONTINUE READING