Diurnal variation for inhibition of eating by bombesin in the rat.

@article{Kraly1983DiurnalVF,
  title={Diurnal variation for inhibition of eating by bombesin in the rat.},
  author={F. Scott Kraly and Leslie A. Miller and James Gibbs},
  journal={Physiology & behavior},
  year={1983},
  volume={31 3},
  pages={395-9}
}
Sprague-Dawley male albino rats ate sweet milk at the midpoint of the day or night phase of a 12:12 light/dark cycle 1 min after IP 0.9% NaCl or synthetic bombesin (BBS; 2-32 micrograms/kg) following 24-hr food deprivation. Exogenous BBS inhibited food intake in a dose-related manner during the day; a linear regression line accounted for 85% of the total variance for percentage suppression of food intake by BBS in 30 min. In contrast, inhibition of eating by BBS at night was not dose-related; a… CONTINUE READING