Diurnal secretion of growth hormone, cortisol, and dehydroepiandrosterone in pre- and perimenopausal women with active rheumatoid arthritis: a pilot case-control study

@article{Blackman2007DiurnalSO,
  title={Diurnal secretion of growth hormone, cortisol, and dehydroepiandrosterone in pre- and perimenopausal women with active rheumatoid arthritis: a pilot case-control study},
  author={Marc R. Blackman and Ranganath Muniyappa and Mildred Wilson and Barbara E Moquin and Howard L Baldwin and Kelli Anne Wong and Christopher Snyder and Michael Magalnick and Shaan Alli and James C. Reynolds and Seth Steinberg and Raphaela T Goldbach-Mansky},
  journal={Arthritis Research & Therapy},
  year={2007},
  volume={9},
  pages={R73 - R73}
}
UNLABELLED Rheumatoid arthritis (RA) is associated with neuroendocrine and immunologic dysfunction leading to rheumatoid cachexia. Although excess proinflammatory cytokines can decrease somatotropic axis activity, little is known about the effects of RA on growth hormone/insulin-like growth factor-1 (GH/IGF-I) axis function. We tested the hypothesis that patients with active RA exhibit decreased GH/IGF-I axis activity. To do so, we conducted a pilot case-control study at a clinical research… CONTINUE READING
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