Diurnal regulation of lipid metabolism and applications of circadian lipidomics.

  title={Diurnal regulation of lipid metabolism and applications of circadian lipidomics.},
  author={Joshua J. Gooley and Eric Chern-Pin Chua},
  journal={Journal of genetics and genomics = Yi chuan xue bao},
  volume={41 5},
The circadian timing system plays a key role in orchestrating lipid metabolism. In concert with the solar cycle, the circadian system ensures that daily rhythms in lipid absorption, storage, and transport are temporally coordinated with rest-activity and feeding cycles. At the cellular level, genes involved in lipid synthesis and fatty acid oxidation are rhythmically activated and repressed by core clock proteins in a tissue-specific manner. Consequently, loss of clock gene function or… CONTINUE READING
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