Diurnal differences in basal and acute stress levels of type I and type II adrenal steroid receptor activation in neural and immune tissues.

@article{Spencer1993DiurnalDI,
  title={Diurnal differences in basal and acute stress levels of type I and type II adrenal steroid receptor activation in neural and immune tissues.},
  author={Robert L Spencer and Andrew H. Miller and H Moday and Maik Stein and Bruce S. McEwen},
  journal={Endocrinology},
  year={1993},
  volume={133 5},
  pages={1941-50}
}
To examine diurnal differences in the proportions of receptors that were occupied and activated by basal and stress levels of corticosterone, we measured available type I (mineralocorticoid) and type II (glucocorticoid) adrenal steroid receptor levels in brain, pituitary, and immune tissues of unstressed and acutely stressed rats at the times of day when basal corticosterone secretion was at its trough [morning (AM)] and peak [evening (PM)]. In general, the estimated adrenal steroid receptor… CONTINUE READING

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