Diurnal cortisol dysregulation, functional disability, and depression in women with ovarian cancer.

@article{Weinrib2010DiurnalCD,
  title={Diurnal cortisol dysregulation, functional disability, and depression in women with ovarian cancer.},
  author={Aliza Z Weinrib and Sandra E. Sephton and Koen Degeest and Frank J Penedo and David Bender and Bridget Zimmerman and Clemens Kirschbaum and Anil Sood and David M. Lubaroff and Susan K Lutgendorf},
  journal={Cancer},
  year={2010},
  volume={116 18},
  pages={4410-9}
}
BACKGROUND Multiple alterations in circadian rhythms have been observed in cancer patients, including the diurnal rhythm of the adrenal hormone cortisol. Diurnal cortisol alterations have been associated with cancer-related physiological processes as well as psychological stress. Here we investigate alterations in diurnal cortisol rhythm in ovarian cancer patients, and potential links with depression, life stress, and functional disability. METHODS Women (n = 177) with suspected ovarian… CONTINUE READING